1. Anti-Inflammatory Effects: Rosa centifolia contains bioactive compounds such as saponins, tannins, quercetin, kaempferol, and cyanidin. These compounds have anti-inflammatory properties that may help reduce inflammation in the lungs. In conditions like asthma or bronchitis where inflammation plays a significant role in symptoms, the anti-inflammatory effects of Rosa centifolia can potentially provide relief. 

2. Antioxidant Activity: The presence of phenolic compounds in Rosa centifolia, including vitamin C, flavonoids, methionine sulphoxide and volatile oils like citronellol and geraniol, contribute to its antioxidant activity. Antioxidants help protect cells from damage caused by free radicals and oxidative stress. By reducing oxidative stress in the lungs, Rosa centifolia may support overall lung health and function. 

3. Antimicrobial Properties: The antimicrobial properties of Rosa centifolia can be beneficial for lung health by helping combat respiratory infections caused by bacteria or viruses. Compounds found in roses such as tannins and essential oils have been traditionally used for their antimicrobial effects. Using rose-based remedies may assist in fighting off pathogens that affect the respiratory system.

4. Respiratory Support: Due to its soothing and healing properties, Rosa centifolia can be used to support respiratory health. Consuming rose petals or extracts may help alleviate symptoms associated with respiratory conditions such as coughs, congestion, or irritation in the lungs.  

5. Lung Cleansing Properties: Rose petals are believed to have cleansing properties that can support detoxification processes in the body, including within the lungs. This cleansing action may help remove toxins and impurities from the respiratory system.

6. Aromatherapy Benefits: The essential oil derived from Rosa centifolia is often used in aromatherapy for its calming and relaxing effects. Inhalation of rose essential oil vapor may promote relaxation and reduce stress levels, which can indirectly benefit lung function by promoting overall well-being. 

7. Anti-cancer Properties: Rose petals have been found to possess medicinal properties that can benefit lung health. Specifically, rose petal extract (RPE) has shown significant effects on lung cancer cells, particularly in inhibiting their proliferation, migration, and invasion. A study investigated the impact of RPE on cancer cells and found that it effectively suppressed the growth of lung cancer cell lines, including A549 lung cancer cells. The inhibitory effects were observed at low concentrations of RPE. The mechanism through which rose petal extract exerts its effects on lung cancer cells involves the downregulation of key mediators involved in cell proliferation, such as PCNA, cyclin D1, and c-myc. Additionally, RPE was shown to suppress the migration and invasion of A549 cells by inhibiting the expression and activity of matrix metalloproteinase-2 and -9 (MMP-2 and MMP-9). These enzymes play a crucial role in breaking down the extracellular matrix during metastasis. Furthermore, the study hypothesized that the suppressive activity of rose petal extract against lung cancer cell proliferation and early metastasis occurs via signaling pathways such as the EGFR-MAPK and mTOR-Akt pathways. These pathways are known to be involved in regulating cell growth, survival, and metastasis in various types of cancers. Incorporating Rosa centifolia into herbal remedies or aromatherapy practices may offer supportive benefits for lung health due to its anti-inflammatory, antioxidant, and antimicrobial properties. Rose petals, specifically in the form of rose petal extract, demonstrate promising medicinal properties for lung health by inhibiting the growth and spread of lung cancer cells through multiple mechanisms involving key signaling pathways.

Antioxidant Effects: Rose petals contain antioxidants that can help neutralize harmful free radicals in the body. These antioxidants may protect joint tissues from oxidative stress and damage, which is important in maintaining joint health and potentially reducing the progression of arthritic conditions. 

Analgesic Properties: The compounds present in rose petals may have analgesic or pain-relieving effects. By acting as natural pain relievers, rose petals could offer relief from joint discomfort associated with arthritis and other inflammatory joint conditions.

Collagen Support: Rose petals are known to contain certain compounds that may support collagen production. Collagen is a vital component of joint cartilage and connective tissues. By promoting collagen synthesis, rose petals could contribute to maintaining joint integrity and function.

Traditional Use in Arthritis: In traditional systems of medicine, including Ayurveda, rose petals have been used for managing inflammatory conditions such as arthritis. The historical use of rose petals for joint ailments suggests a long-standing recognition of its potential benefits for joint health.

In conclusion, rose petals from Rosa centifolia exhibit anti-inflammatory, antioxidant, analgesic, and collagen-supporting properties, making them potentially beneficial for promoting joint health and alleviating symptoms associated with various joint disorders, including arthritis.

1. Anti-Inflammatory Activity: Rose petals, specifically Rosa Centifolia, have been found to possess skin anti-inflammatory properties. Studies have shown that rose petal extract (RPE) can reduce solar UV-induced inflammation in the skin. This effect is attributed to the ability of RPE to decrease the expression of inflammatory markers such as COX-2 and various cytokines. Additionally, RPE has been shown to attenuate the activation of signaling pathways like MKK4-JNK, MEK-ERK, and MKK3-p38 associated with cytokine production, thereby reducing skin inflammation caused by UV exposure. These effects were attributed to the antioxidant activity of RPE, as it displayed radical scavenging properties and high levels of anthocyanins, polyphenols, and flavonoids.

2. Antioxidant Activity: The antioxidant activity of rose petal extract contributes significantly to its medicinal properties on the skin. RPE exhibits strong radical scavenging capabilities and high oxygen radical absorbance capacity (ORAC), which help in combating oxidative stress induced by reactive oxygen species (ROS) generated from factors like UV radiation. The presence of anthocyanins, polyphenols, and flavonoids in RPE further enhances its antioxidant potential, protecting the skin from damage caused by ROS.  

3. Protection Against DNA Damage: Due to its antioxidant properties, rose petal extract can potentially protect skin cells from DNA damage caused by ROS. By neutralizing free radicals and reducing oxidative stress, RPE may help prevent mutations and cellular damage that can lead to premature aging or other skin conditions.

4. Anti-Aging Effects: The antioxidant and anti-inflammatory properties of Rosa Centifolia petals make them beneficial for combating signs of aging on the skin. By reducing inflammation and oxidative stress, rose petal extract can help maintain skin health, elasticity, and firmness, thereby contributing to a more youthful appearance.

5. Moisturizing and Soothing: In addition to its anti-inflammatory and antioxidant effects, rose petal extract is known for its moisturizing and soothing properties. It can help hydrate the skin, reduce redness or irritation, and promote overall skin comfort.

6. Wound Healing: Some studies suggest that rose petals may have wound healing properties when applied topically. The anti-inflammatory and antioxidant components in rose petal extract could aid in promoting tissue repair and regeneration, potentially accelerating the healing process for minor wounds or skin irritations. 

7. Biological Activities: The Rosa plant species, known for its medicinal uses against conditions like nephritis and hemorrhoids, contains various beneficial compounds such as terpenes (glycosides), flavonoids, and anthocyanins. Studies have highlighted the antioxidant potential of rose petals due to their phenolic acids, flavonols, and anthocyanins content. These bioactive components contribute to the overall medicinal properties of rose petals on the skin.

In conclusion, Rosa Centifolia petals exhibit a range of medicinal properties that benefit the skin, including anti-inflammatory, antioxidant, protective against DNA damage, anti-aging effects, moisturizing and soothing qualities, as well as potential wound healing capabilities.

1. Anti-inflammatory Activity: Rosa centifolia has demonstrated anti-inflammatory effects, which can be beneficial in conditions involving inflammation such as sore throats, arthritis and joint pain. 

2. Antiarthritic Activity: Studies have shown that extracts from Rosa centifolia exhibit antiarthritic activity, making it potentially useful in the management of rheumatoid arthritis (RA) and joint disorders.

3. Antioxidant Properties: The plant contains compounds with antioxidant properties, which can help combat oxidative stress and protect cells from damage caused by free radicals.

4. Analgesic Effects: Rosa centifolia may possess analgesic properties, contributing to its traditional use in alleviating pain associated with various conditions.

5. Immunomodulatory Effects: It is suggested that Rosa centifolia may have immunomodulatory effects, potentially influencing the immune response and inflammatory processes in the body.

6. Wound Healing Abilities: The plant has been used traditionally for wound healing purposes, indicating its potential role in promoting skin regeneration and tissue repair. 

7. Antibacterial: Rose petals exhibit antibacterial properties, which can help in fighting off harmful bacteria and preventing infections. 

8. Anti-viral: Rose petals contain compounds that have antiviral properties, potentially aiding in combating viral infections.

9. Skin Health: Rose petals are beneficial for skin health due to their antibacterial, antiseptic, and anti-inflammatory properties. They can help soothe irritated skin, reduce redness, and promote healing of wounds.

10. Astringent: The astringent properties of rose petals make them beneficial for toning and tightening the skin, as well as reducing inflammation.

11. Cardioprotective Potential: Some studies suggest that components of Rosa centifolia may have cardioprotective effects, possibly benefiting heart health and circulation. 

12. Diuretic: Rose petals act as diuretics, promoting urine production and aiding in detoxification processes within the body. 

13. Digestive Health: The tannins found in rose petals can aid in digestion by promoting the growth of beneficial gut bacteria and reducing inflammation in the digestive tract. Rose petals may help manage conditions like gastritis and ulcers.

14. Respiratory Health: Rose petals have been traditionally used to alleviate respiratory issues such as coughs, asthma, and bronchitis due to their expectorant properties that help clear mucus from the airways.

15. Cardiovascular Benefits: Compounds like quercetin and kaempferol present in rose petals have been linked to cardiovascular health by helping to lower blood pressure, reduce cholesterol levels, and improve heart function.

16. Mood-Enhancing (Anti-depressant): The aroma of roses is known to have mood-enhancing effects, potentially acting as an antidepressant and promoting feelings of well-being. 

17. Stress Relief: The aroma of rose petals is known for its calming effects on the mind and body. Rose petal tea or aromatherapy with rose essential oil can help reduce stress, anxiety, and promote relaxation.

18. Aphrodisiac Properties: In traditional medicine systems, Rosa centifolia has been associated with aphrodisiac properties, which may have implications for sexual health and vitality. 

19. Sedative Properties, Stress Relief: The aroma of rose petals is known for its calming effects on the mind and body. Rose petals are known for their calming effects, making them useful in soothing nerves and reducing anxiety and stress.

Overall, the diverse medicinal properties of Rosa centifolia make it a valuable botanical resource with potential applications in various health conditions and wellness practices. Rose petals from Rosa centifolia offer a wide range of medicinal properties that make them valuable for various health benefits including antioxidant effects, anti-inflammatory actions, skin health promotion, digestive support, cardiovascular benefits, respiratory health improvement, stress relief, among others. These medicinal properties make rose petals versatile for addressing a range of health issues, from physical ailments like urinary tract infections to emotional concerns like anxiety and depression. 

Authoritative References Used:

1. Medical Medium & The Chestnut School of Herbal Medicine
2. “In vivo antiarthritic activity of Rosa centifolia L. flower extract” - PubMed Central (PMC)

Top 12 Authoritative Sources Used:

1. PMC (PubMed Central) - In vivo antiarthritic activity of Rosa centifolia L. flower extract: This study investigates the antiarthritic activity of Rosa centifolia L. flower extract using animal models. It provides scientific evidence supporting the traditional use of rose petals for joint pain and rheumatoid arthritis.

2. Bhavprakash Nighantu: A classical Ayurvedic text that provides information on the medicinal properties of herbs including Rosa centifolia (rose). It offers insights into the Ayurvedic perspective on the therapeutic uses of roses.

3. The Bhavprakash Nighantu with elaborated Hindi commentary by Padmashri Prof. K.C. Chunekar: An edition from 1998 containing detailed information on various herbs including roses with specific references to their medicinal properties according to Ayurveda.

4. Indian Journal of Pharmacology 
5. National Center for Biotechnology Information (NCBI) 
6. International Agency for Research on Cancer 
7. Cell Signaling Technology
8. Santa Cruz Biotechnology
9. International Journal of Pharmacy and Pharmaceutical Sciences (Al-Snafi, A. E., 2016)
10. International Journal of Ayurveda Research (Chanchal, D. K., Patel, K. R., & Patel, D. K., 2011)
11. International Journal of Pharmacy and Pharmaceutical Sciences (Mishra, A. K., Mishra, A., & Chattopadhyay, P., 2011)
12. World Health Organization (WHO)